Peptide RitengaTe whakahiatoRatonga
Hangzhou Haere Runga Peptide Biotech , i whakapumautia i te tau 2014, he a Hangarau Hangarau-Motute tohungatanga ki te rangahau, te whakawhanaketanga me te hanga peptides me nga päröpü whai hononga.
Ko te kamupenepokapū rangahau peptidekei te Takiwa o Qiantang i tenei waof Hangzhou, e hipoki ana i te waahanga neke atu i te 3,000 mita tapawha.Ko tekamupene's wheketere kei te No.24, Haitian Road, Shangyu District, Shaoxing pa, Zhejiang kawanatanga.Kei reira ano e rua nga tipu mahi tahi, kotahi mohangahanga GMP peptide arumoni kei rotoKo Anji te rohe o Zhejiang, Ko tetahi mo te API ngota iti kei rotoYuncheng pa o Shanxi kawanatanga.Ka riro tatouhe hinonga hangarau teitei matawhānui, te whakauru i te rangahau, te tauine pairati, te hokohoko me nga hokonga o te ao.
Kei te kamupenemutu100kaimahi,a kuawhakawhanakehia ake i40 rongoā pakekepeptides,nui atu i10 patent tenengakua whakamanahia.Tia tau te kaha whakaputais ki runga ki100 kirokaramu, te maha o nga peptides ritenga kua i eke ki runga ake i te 20,000.Ka taea e matou te whakarato ratonga peptide kotahi-mutu mai i te rangahau (mg) ki te hokohoko (KGs).
Rarangi Whakarerekē Peptide
N-whakarerekētanga kāpeka
| {N-Me-Ala} | {N-Me-Asp} | {N-Me-Glu} | {N-Me-Ile} |
| {N-Me-Leu} | {N-Me-Met} | {N-Me-Nle} | {N-Me-Nva} |
| {N-Me-Phe} | {N-Me-Ser} | {N-Me-Thr} | {N-Me-Tyr} |
| {N-Me-Val} | {Sar} | N-Me-Arg | N-Me-Asn |
| N-Me-beta-Ala | N-Me-Gln | N-Me-Lys | N-Me-Trp |
C-whakarerekētanga kāpeka
| {Mono Disulfide piriti} | {Pūrua Disulfide piriti} | {Triple Disulfide bridge} |
| {piriti Disulfide tupurangi} | {Same Seq.piriti Inter-Disulfide } | {piriti Inter-Disulfide rereke} |
| {Amide cyclic (mutunga)} | {Amide cyclic (Side chain)} | {Rini taha taha Amide cyclic} |
| {Thioester cyclic} | {lactone cyclic} | {Sec cyclic} |
Nga waikawa amino rereke
| {2-Aze} | {3-Aze} | {5,5-Dime-Pro} |
| {5-ASA} | {Abu} | {Ac-Lys} |
| {Aib} | {Beta-Asp} | {Bpa} |
| {Cha} | {Chg} | {Cit} |
| {Cpg} | {Cys(Acm)} | {Cys(Bzl)} |
Ko nga peptides kua tapaina te Isotope
| Lys(13C6,15N2) | Ile(13C6,15N) |
| Leu(13C6,15N) | Val(13C5, 15N) |
| Arg(13C6, 15N4) |
Ko nga whakarerekëtanga peptide karekau/FRET takirua
| Biotin- | Dansyl- | Peptide fluorecent kua tinei |
| Biotin-Ahx- | Dansyl-Ahx- | Dabcyl |
| 5-FAM- | Cy3- | Dabcyl / Glu(Edans)-NH2 |
| 5-FAM-Ahx- | Cy5- | Dansyl- |
| FITC- | MCA/DNP | Dansyl-Ahx- |
| FITC-Ahx- | AMC | Edans / Dabcyl |
Peptide Conjugates
| BSA(-COOH o C tauranga | KLH(-NH2 o te kāpeka N) | OVA(-COOH o te tauranga C) |
| BSA Conjugation on Cys | KLH Conjugation on Cys | OVA(-NH2 o te kāpeka N) |
| OVA Conjugation on Cys |
Whakahauora
| {pSer} | {D-pSer} |
| {pTyr} | {D-pTyr} |
| {pThr} | {D-pThr} |
Ētahi atu whakarerekētanga(PEGylation, Cyclic modifications, Disulfide Bridges)
| PEGylation | Nga whakarerekētanga porohita | Nga Piriti Disulfide |
| {Mini-PEG1} | Mahunga ki te hiku hurihanga | {Mono Disulfide piriti} |
| {Mini-PEG2} | {Pūrua Disulfide piriti} | |
| {PEG-11} | {Triple Disulfide bridge} | |
| {PEG-12} | {piriti Disulfide tupurangi} | |
| …… | …… | …… |