He kupu whakataki poto mo te tidulutide

Te mahi a te tidulutide Gattex (teduglutide)

Ko te Teduglutide he tairitenga tangata mo te glucagon-like peptide-2 (GLP-2), he peptide i hunahia e nga pūtau L i roto i te whekau.E mohiotia ana te GLP-2 ki te whakapai ake i te rere toto intestinal me te tomokanga me te aukati i te whakaputanga waikawa pekitīlia.Mo nga tohu o te lu peptide me te peptide receptor 2 tauira glucagon, te ahua o te insulin-rite tipu i roto i nga pūtau endocrine intestinal, nga pūtau epithelial o te muka uaua, te submucosa me te tu myenteric i waenga i nga neuron intestinal.Ko te whakahohenga o enei kaiwhakawhiwhi ka puta te whakaputanga o nga momo purongo rereke, tae atu ki te insulin-like growth factor (IGF) 1, pūtau tipu tipu hanga hauota waikura me te cutin cell growth factor (KGF).

Ko te Tidulutide, he rite ki te glucagon-like peptide 2 (GLP-2), ka whakaheke i te putunga o te kopu me te paopaotanga me te whakahaere i te tipu, te whakaputa uri me te whakaora i nga pūtau arai whekau.Ko te peptide te whakanui i te tapeke o enei pūtau, ka taea te whakanui ake i te whakauru o te kohanga iti, te whakaiti i te matere.Ka taea te rongoa i te mate pukupuku poto i roto i nga pakeke.Ko te raau taero ko te rongoa tuatahi ki te onge engari tino ngoikore.

He kupu whakataki poto mo te tidulutide

Te tātai rāpoi matū o te tidulutide

Tawhā taketake

Ingoa: mo te c peptide (Teduglutide)

Tau: GT – F027

Nama CAS: 197922-42-2

Raupapa: His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn- Trp-Leu-Ile-Gln-Thr-Lys- Ile-Thr-Asp

tātai rāpoi: C164H252N44O55S

Te taumaha ngota: 3752.08248